Tummy FAQs

GOOy CHEWy TUMMY: Frequently Asked Questions (FAQ).

GOOy CHEWy HONEY plus TUMMY Questions

Probiotics : Multi Vs Single Bacteria Strain ? More CFU Vs Less ?

More Bacteria Strains is Not always Better. Especially, When it comes to Probiotics.

More CFU is not always Better. Especially when it comes to BC30

With Probiotics becoming more and more a part of our healthy lives, there has been a great deal of discussion regarding the necessary CFU supplementation levels of Probiotics ( CFU, or Colonizing-Forming Units, whether per dose or per day ) and whether multiple verses single bacteria strain Probiotic use is an issue or not.

Research and clinical trials should guide this debate. It is sometimes stated that “If supplementing 1 billion cells is good, then supplementing 1 trillion cells is even better.” This may not be true; in fact, this could lead to serious health consequences depending on the type(s) of bacteria involved. Several strains have been shown to be toxic at high dose levels and/or cause adverse health effects.

Regarding Colony Forming Units ( CFUs ), the main reason we have the “CFU Level Wars” is that in a lot of cases companies claim very high CFU levels because they know that a vast majority of the cells they are providing will not survive before reaching the gastrointestinal tract.

In some cases, less than 0.1% survives. Regarding the Probiotic strain used in GOOy CHEWy, research indicates that up to 78% of the cells reach the intestines. Armed with this data we can recommend a CFU level that is efficacious and is clinically substantiated without excessive over-formulation.

The supplementation of a single strain versus multiple strains is also an area of great debate. Again it comes down to science. Each individual strain has a particular utility that is unique to that specific strain. Unless multiple strain formulations have been tested in controlled clinical trials (and very, very few have been) there is no evidence that the strains will perform the same way in the presence of other strains as they do alone. So, it’s not really a matter of one strain plus another strain (or more) equals the combined benefits of them all. Unless the multiple strain combination is studied together we do not believe that it is scientifically appropriate or valid to assume an additive benefit of all the strains together. Ganeden ( the company that produces the Probiotic in GOOy CHEWy ) has a single strain that by itself has been shown to have many benefits and currently has 13 published papers on this exact strain supporting these benefits.

For further Information regarding GOOy CHEWy’s Probiotic BC30, Check out these Links:

http://www.ganedenbiotech.com/

http://www.ganedenbc30.com/

Why is BC30 Probiotic Strain Bacillus Coagulans built to Last ?

GOOy CHEWy TUMMY > Probiotic BC30 Hardened Structure / Spore Forming

Chosen to Survive for Your Digestive Health.

Bacillus coagulans is a species of beneficial bacteria, or probiotics; GanedenBC30® is the brand name for the probiotic strain, Bacillus coagulans GBI-30, 6086.

GanedenBC30® is designed by nature to survive strong stomach acid and thrive so more probiotic cells can help support your digestive system.

What makes GanedenBC30® different from other probiotics ?

GanedenBC30® is unique because inside each cell is a hardened structure, or spore, which is similar to a seed. This spore, or seed, serves as a natural protective shield against the heat and pressure of manufacturing and the strong acids in your stomach to arrive alive and then thrive in your intestines-their intended target.

Other traditional probiotic bacteria such as lactobacillus, acidophilus and bifidobacteria are not able to form these protective spores, making them more vulnerable to manufacturing processes and stomach acid

GOOy CHEWy TUMMY & BC30: The Probiotic that Survives !

GOOy CHEWy TUMMY contains a unique strain of probiotic called BC30. BC30 is protected by an outer layer protein which ensures its survival in significant numbers to reach the digestive tract where it can have the greatest health benefit. It then can take its place in both the small and large intestine where it promotes digestive and immune health. BC30 cells have much higher survival rates than some other probiotic capsules, pills, and yogurts and are also prolific colonizers.

BC30 Survives 10 Times Better

Your digestive system is home to 10,000 microbial species or microflora. Probiotics are good microflora—usually living bacteria but also yeast and other organisms—that help maintain a healthy microbial environment and help keep your digestive system happy.

Many other probiotics don’t survive the harsh acidic stomach environment and are destroyed. BC30 (Bacillus coagulans), the unique strain of bacteria in GOOy CHEWy, has a naturally occuring protective shell surrounding each cell so it can withstand the harsh acidity of your stomach. With a survival rate 10 times higher than other probiotics, including yogurt, BC30 is better able to reach your intestines alive and promotes a healthy digestive tract.

Spore forming probiotic organisms such as Ganeden BC30 are the only probiotics that have the ability to withstand harsh manufacturing processes, especially those required to make hot tea, coffee, cereal or GOOy CHEWy’s ! The effectiveness of these organisms can be linked to its naturally occurring layer of organic material (spore), which protects the genetic core of the bacteria throughout the manufacturing process and the transit in to the gut. Non-spore forming probiotics, such as Lactobacillus and Bifidobacterium, are unable to form this protective layer, making them much more vulnerable to manufacturing conditions.

What is EpiCor ?

YOU Tube EpiCor Video

http://www.youtube.com/watch?v=bw9TrsniCzs#t=44

Scientific Mode of EpiCor Action Summary on All Clinical Studies

GOOy CHEWy TUMMY…

Much, Much more than a Honey Treat ..

Innate & Adaptive Immune Health

Allergy / Asthma

AntiOxidant

Inflammation

GUT Health / Immunity

Scientific Mode of EpiCor Action Summary on All Studies

Biochemical Markers Observed in EpiCor Studies

Larry E. Robinson, Ph.D. and Stuart Reeves, Ph.D., ARCS, Scientific Affairs

A major portion of Embria’s research on EpiCor has been with double-blind, placebo-controlled human trials, looking at clinical endpoints. These results were aimed at demonstrating statistically significant improvements of the consumer’s health, and have been published in peer-reviewed Medline-indexed journals. Although reduction in symptoms of upper respiratory track infection (URTI) and allergies were the main thrust of the research, the importance of clinical biomarkers in demonstrating the causes of these beneficial effects was also recognized, and some of these results are reported below. All effects are in vivo and on healthy human adults unless otherwise stated.

1) INNATE AND ADAPTIVE IMMUNE SYSTEM

Significantly increases Natural Killer (NK) Cell activation in vivo(1) and in vitro(2)

Significantly increases NK Cell activation in less than two hours post-consumption(3)

PHYSIOLOGY: NK cells are a type of white blood cell critical to the innate immune system. They provide a rapid immune response to virally infected cells as well as malignant cells. In many cases the NK cells will destroy the infected or malignant cell before the viral infection or malignant tumor can be established. Even if an infection becomes established, NK cells are also known to play a role in the slower acting but more specific adaptive immune response.

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Significantly increases secretory salivary IgA (sIgA) versus placebo(1,4)

PHYSIOLOGY: sIgA is the main immunoglobulin (antibody) found in mucous secretions, including tears, saliva, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is a major component of the body’s defense against invading pathogens.

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Serum IgG increased over the five-week consumption period in both groups, with the trend strongest in the EpiCor group (1)

PHYSIOLOGY: Serum IgG makes up about 75% of the antibodies found in blood. It is an important part of the immune system’s ability to fight infections of body tissues. It binds many kinds of pathogens — including viruses, bacteria, and fungi — and protects the body against them using several immune mechanisms.

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Increases B cell activation in vitro(2)

PHYSIOLOGY: B cells are an essential component of the human adaptive immune system. Their principal function is to make antibodies against antigens.

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Significant increase in Interferon-gamma (IFN-γ)(3)

PHYSIOLOGY: IFN-γ is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFN-y is now thought to have pleiotropic effects and thus can have both promoting and suppressive roles in autoimmunity.

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ALLERGY / ASTHMA

Strong trend toward reduction of eosinophils in EpiCor group versus placebo(4)

PHYSIOLOGY: Blood levels of eosinophils are commonly elevated in people with asthma and other allergic diseases.

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Significant decrease in lymphocytes in nasal smears in EpiCor group versus placebo(4)

PHYSIOLOGY: Increased lymphocytes would be expected in the nasal smears of allergy sufferers.

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Trend toward relative decrease in serum IgE versus placebo(1,4)

PHYSIOLOGY: Pollen binds to IgE antibodies present on the mast cells of allergy sufferers. The mast cells, and similar cells like basophils activate to release chemicals, including histamine, into the blood vessels and tissues. The binding of histamine to histamine receptors produces the effects of inflammation to surrounding tissues and causes nerve stimulation, leading to symptoms of itchy, watery eyes, sneezing, runny nose, and itching of the nose and throat.

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Significant decrease in PGE2 levels by 31%(5)

PHYSIOLOGY: Prostaglandins, including PGE2, are also produced in large amounts during allergen exposure, and some conventional medicines reduce PGE2 levels as part of their respective mechanisms of action.

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Significant decrease in NGF by 22%(5)

PHYSIOLOGY: Excessive production of NGF was found in past studies of allergic rhinitis patients.

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Trend toward lower serum basophil percentages(4)

PHYSIOLOGY: The mast cells, and similar cells like basophils activate to release chemicals, including histamine, into the blood vessels and tissues, which leads to allergy symptoms.

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Dose dependent inhibition of LPS-induced nitric oxide (NO) with EpiCor, while positive control increased NO (in vitro bioassay)(6)

PHYSIOLOGY: In medicine, exhaled nitric oxide can be measured in a breath test to diagnose or monitor asthma or other conditions characterized by airway inflammation.

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Total white blood cell count remained constant in the EpiCor group, whereas there was a mild trend towards an increase in white blood cells in the placebo group(1)

PHYSIOLOGY: While blood cells tend to proliferate in people due to the onset of seasonal allergies.

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ANTIOXIDANT

Significant increase in serum antioxidant protection seen two hours post-consumption(3)

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GUT HEALTH AND RELATIONSHIP BETWEEN GUT HEALTH AND IMMUNITY

EpiCor modulates the gut microflora, increasing the proportion bifidobacteria and lactobacilli (B&L)

PHYSIOLOGY: B&L are lactic acid-producing bacteria constituting a major part of the intestinal microflora in humans and other mammals. The most important role of the microflora, from the point of view of the host, is probably to act in colonization resistance against exogenous, potentially pathogenic, microorganisms.(7)

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Increases production of butyrate

PHYSIOLOGY: Butyrate is the major energy source for the intestinal epithelial cells, is considered to have anti-inflammatory effects, and has been studied for its role in nourishing the colonic mucosa and in the prevention of cancer of the colon.(8)

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Decreases production of proinflammatory cytokines

PHYSIOLOGY: The change in composition of the microbial community of the gut caused a reduction in the production of inflammatory cytokines IL-8 and IL-1b in a model of the gut lining (9).

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Individual IL-10 levels were increased after EpiCor consumption, while they remained unchanged in the placebo group(1)

PHYSIOLOGY: Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

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Significantly increases secretory salivary IgA (sIgA) versus placebo(1,4)

PHYSIOLOGY: In a healthy person, sIgA inhibits the colonization of pathogenic bacteria in the gut, as well as the mucosal penetration of pathogenic antigens. At least 80% of all the body’s plasma cells, the source of sIgA, are located in the intestinal lamina propria throughout the length of the small intestine.(10)

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INFLAMMATION

EpiCor treated mice had significantly lower arthritis scores versus placebo(5)

Arthritic mice showed significant increase in IFN-γ levels in control mice versus mice fed EpiCor(5)

PHYSIOLOGY: IFN-γ is one of the primary endogenous mediators of inflammation and immunity. IFN-γ has been considered an autoimmune disease promoting or pro-inflammatory cytokine, as also suggested from the collagen-induced arthritis model. IFN-γ is now thought to have pleiotropic effects and thus can have both promoting and suppressive roles in autoimmunity.

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Arthritic mice showed significant increase in levels of immune complexes in control mice versus mice fed EpiCor.

PHYSIOLOGY: Increased levels of immune complexes are associated with autoimmune diseases.

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Significant decrease in NGF by 22%(5)

PHYSIOLOGY: Increases in NGF are associated with discomfort and pain with inflammatory responses because it impacts mast cells and afferent neurons. NGF is such a profound primary mediator of chronic pain that even vaccine research has been initiated in this area of medicine.

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Rat paw edema severity and PGE2 levels were significantly reduced by approximately 50% and 31% respectively by consumption of EpiCor(5)

PHYSIOLOGY: A major mediator of the localized inflammatory response in this model is the proinflammatory prostaglandin PGE2, which has a role in other medical conditions as well. For example, in autoimmune diseases such as rheumatoid arthritis, PGE2 has a pro-inflammatory function.

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Individual IL-10 levels were increased after EpiCor consumption, while they remained unchanged in the placebo group(1)

PHYSIOLOGY: IL-10, also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.

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References

G.S. Jensen et al: “A double-blind placebo-controlled randomized pilot study: consumption of a high-metabolite immunogen from yeast culture has beneficial effects on erythrocyte health and mucosal immune protection in healthy subjects.” The Open Nutrition Journal (2008) 2, 68–75

G.S. Jensen et al, “An anti-inflammatory immunogen from yeast culture induces activation and alters chemokine receptor expression on human natural killer cells and B lymphocytes in vitro,” Nutrition Research (2007) 27, 327-335

G.S. Jensen et al, “Antioxidant Bioavailability and Rapid Immune-Modulating Effects After Consumption of a Single Acute Dose of a High-Metabolite Yeast Immunogen: Results of a Placebo-Controlled Double-Blinded Crossover Pilot Study,” J Med Food (2011) 14, 1–9

M. A. Moyad et al., “Immunogenic yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled trial,” Advances in Therapy (2009) 26, 795–804

M. Evans, S. Reeves, L. Robinson, “A Dried Yeast Fermentate Prevents and Reduces Inflammation in Two Separate Experimental Immune Models,” Evidence-Based Complementary and Alternative Medicine (2012), Article ID 973041 (on line)

Nitric Oxide assay. Natural Remedies, Private LTD (2005)

Dwight King, KJ Girling, “Gut flora in health and disease”. The Lancet (2003) 361, 1831

Pryde SE, Duncan SH, Hold GL, Stewart CS, Flint HJ, “The microbiology of butyrate formation in the human colon,” FEMS Microbiol Lett. (2002) 217, 133-139

Reeves et al, “Establishment of prebiotic properties and protection against inflammation of a yeast-based food supplement, using an integrated in vitro approach”. Presented at IFT11 (2011), New Orleans, LA

O. Adolfsson et al, “Yogurt and gut function,” (ABSTRACT), American Society for Clinical Nutrition (2004)

What are the Beneficial Immune Effects on Gut Health produced by EpiCor^{® ?}

[] Summary:

The gut is extremely important for proper immune health.

Gut-Associated Lymphoid Tissue (GALT) comprises a large part of the immune system.

Studies indicate that EpiCor appears to support gut health through a variety of mechanisms:

EpiCor acts as a prebiotic, which helps explain part of its mode of action as an immune modulator system strengthener.

The model used an established human gut flora inoculum and showed that EpiCor significantly increased the levels of butyrate, a short chain fatty acid (SCFA) that has been shown to be beneficial for gut immune health.

EpiCor significantly increased the levels of beneficial bacteria (bifidobacteria and lactobacilli) over the control.

Levels of secretory IgA have been shown to significantly increase with EpiCor vs. placebo in human clinical trials. This important immunoglobulin present in mucosal membranes is vital in our body’s first line of defense against pathogens.

EpiCor contains mannan-oligosaccharides (MOS) and ß-glucans. Research has repeatedly demonstrated the beneficial effects of these oligosaccharides for gut immune health.

Results show that the immune and prebiotic effects of EpiCor are complementary and help to improve gut health.

[] Effect of EpiCor on Bacterial Populations in the Model System

Study results show the ability of EpiCor to increase the levels of these beneficial bacterial groups, bifidobacteria and lactobacilli, as compared to the cellulose control. These results suggest EpiCor acts as a prebiotic, with effects similar to inulin and FOS. These additional gut health benefits, combined with data from other studies performed with EpiCor, may further explain why EpiCor helps the body achieve immune balance.

[] EpiCor has been shown in multiple published studies to support both the innate and adaptive parts of the immune system. However, due to the complex interactions between the immune system and the digestive system (GALT), it seemed very likely that EpiCor would positively affect gut health.

The model used to study the GUT benefits of EpiCor was a multistage simulator of the human digestive system, using an established human gut flora inoculum. The system is designed to screen products for prebiotic and probiotic activity. To test for prebiotic effects, the relative amounts of SCFA levels and changes in populations of bifidobacteria and lactobacilli were measured. During this trial, cellulose was used as a negative control, and fructooligosaccharide (FOS) and inulin were used as positive controls.

Definitions

Probiotic: Live microorganisms which when administered in adequate amounts confer a health benefit on the host.

Prebiotic: A prebiotic is a selectively fermented ingredient that results in specific changes in the composition and/or activity of the gastrointestinal microbiota, thus conferring benefit(s) upon host health.

Synbiotic: The term synbiotic is used when a product contains both probiotics and prebiotics.

How does GOOy CHEWy Tummy’s EpiCor Ingredient Help my Health ?

The importance of natural killer (NK) cell activity is discussed in many internet articles. NK cells are your immune system’s first line of defense against invading pathogens or cancer cells. Researchers found that NK cell activity increased four-fold following continued ingestion of the concentrated yeast culture. This increased efficiency allowed the immune system to perform at superior levels with fewer NK cells – sparing the body the stress and expenditure of having to produce more NK cells.

Also, improved the ratio of immune helper cells to suppressor cells. In the simplest terms, helper cells (CD4 cells) are crucial in coordinating the response of the immune system to pathogens. They activate other immune cells and stimulate the production of antibodies. Suppressor cells (CD8 cells), on the other hand, help maintain a balance so your immune system doesn’t “over-react.” They stop an attack. Individuals taking the yeast culture also exhibited higher levels of antibodies, indicating their immune systems were more effective.

A most important findings of all has to do with levels of what’s called IgA. The increase in antibiotic-resistant respiratory diseases has become an ever-increasing, worldwide concern. It’s not if we’ll have a worldwide respiratory epidemic, it’s just of matter of when. TB, SARS, and bird flu are just a few examples of serious threats beginning to emerge. Since this flu strain and other viruses and bacteria mutate, there is little hope any vaccine will afford protection. If one of these pathogens becomes virulent and able to pass from human to human, we’re going to need more than just promises of a possible vaccine.

Immunoglobin A (IgA) is an antibody found in the mucosal lining of the respiratory and digestive tracts and an indicator of mucosal barrier strength. The research showed that the ingestion (even if through inhalation) of this fermented yeast culture was directly associated with astoundingly higher levels of IgA. This was obviously one of the determining factors as to whether one contracted an infectious disease or went years or decades without any infection whatsoever. This will be a deciding factor in who survives and who succumbs if we’re ever hit with a virulent worldwide pandemic. Laboratory findings noted that the level of immune markers in individuals ingesting this product was much higher than seen in other humans. This, in turn, gave those people’s immune systems significantly more ability to kill viruses, bacteria, and tumor cells.

Like many other natural products, yeast cultures are very complex – and there are unquestionably dozens of components that contribute to its efficacy.

The compounds in the human product developed by EpiCor included some surprises:

Selenium, a powerful antioxidant. Insufficient selenium in the diet allows viruses to mutate, which helps explain why we see most of the flu viruses arising from areas within China.

Squalene, a steroid precursor normally found in only a few species of sharks and a few plants. It’s one of the key immune-boosting components responsible for the marketing of shark liver oil.

Resveratrol, one of the true “anti-aging” compounds, which is normally found in grape skins and red wine. They’ve also found it contains all the primary minerals, trace minerals, amino acids, and several B vitamins, as well as other beneficial compounds normally found only in foods like blueberries and green tea. Ingestion of the yeast culture increases glutathione levels as well. There is a direct relationship between your glutathione levels and health and longevity. It’s typical for glutathione levels to decrease as a person ages, but individuals who are able to maintain higher levels of glutathione live longer and healthier lives.

The lab tests have also revealed that the yeast culture has over three times the antioxidant capacity of any known food. The oxygen radical absorbance capacity (ORAC) of the product was shown to be 614, which is almost four times the highest ORAC-value food, black raspberries, which have a value of 164

Proven Safety… All of the studies conducted have revealed this cultured yeast product is non-toxic and safe. Extensive toxicology studies have been undertaken, and even at extremely high dosages there has never been any indication of any side effects. It has also been tested for pesticides (over 139 of the most common) and toxic residues – and it contains neither. Additional tests have been performed to determine if it interferes with over-the-counter or prescription medications – and it doesn’t.

One concern for many people has to be the fact that the product is a yeast culture. Individuals bothered with systemic infections from the yeast Candida albicans are hesitant about including any yeast products in their diet. Yeast infections have been linked to numerous chronic health problems. It’s important to remember, however, that this product is a dried, fermented yeast culture. As opposed to live yeast, this culture contains the fermented metabolites of a once-live colony of yeast, as well as the dead yeast itself and the residue of the medium it was grown on. It doesn’t transfer live yeast organisms to your GI tract, but instead facilitates and increases the growth of the existing beneficial bacterial flora. Most everyone has Candida albicans and dozens of other potential pathogens living in their lower GI tract, few of those people experience any problems – because their level of beneficial bacteria is sufficient to keep the pathogens in check.

Research has shown that much of our immunity and ability to survive is stimulated by a limited exposure to a wide variety of these controlled pathogens. In effect, components of this product work as a “prebiotic” to feed the beneficial bacteria in your gut. (Don’t forget to keep taking your probiotics and fermented food to replenish the beneficial bacterial as well.) Beneficial bacteria produce secondary by-products or “metabolites” inhibit the growth of harmful viruses, bacteria, fungi, and other pathogens. The yeast culture also provides its own, very potent metabolites.

Very minute levels (one part per billion) of this product have been shown to totally inhibit the growth of E. coli, the bacteria associated with food poisoning. The combination of dead yeast and metabolites increases mass in the gastrointestinal tract, improving fiber and protein digestion by supplying a long list of various nutrients and enzymes.

Using this product on a regular, continuous basis, the strongest attributes is the fact it balances the immune system rather than stimulates.

Individuals who suffer from what are called autoimmune diseases can make their condition worse by taking anything that overstimulates their immune system. Their immune systems have lost their ability to distinguish normal healthy cells from pathogens (bacteria, viruses, fungi, parasites) and will readily attack healthy cells.

For example, in type 1 diabetes, the immune system destroys the islet cells in the pancreas that produce insulin. In rheumatoid arthritis it attacks the joints. Other examples of autoimmune disease include multiple sclerosis (MS), systemic lupus erythematosus (SLE), and Graves disease.

This is a product you can (and should) take on a consistent basis to help keep your immune system balanced without overstimulation.

Since it’s not a stimulant, it wouldn’t be used as a “treatment” for some acute problem like a cold or flu. Instead, it’s something that can be taken continuously to prevent a cold, flu, or other infection from happening in the first place. It’s a maintenance-type product that has a long history of being safe and effective for long-term use.

GOOy CHEWy TUMMY “Nutritional Label “

GOOy CHEWy TUMMY “Ingredient Label”

Use Frequency for GOOy CHEWy HONEY plus TUMMY

Why is it Important to keep GOOy RELIEF & TUMMY Refrigerated ?

While Popping a GOOy or Two in your Purse, Brief Case, Back Pack or School Bag for the Day’s Consumption is OK, GOOy CHEWy feels that Refrigeration upon Arrival, and until Fully Consumed is the Best Measure that can be taken to keep GOOy’s Ingredients their Freshest.

How long do I continue a daily STRESSed Amount of GOOy CHEWy TUMMY ?

GOOy CHEWy believes that GUT Mediated Immunity / Health / Balance is one of the CornerStones of Overall Health.

When you GUT is Out-of-Balance / UnHealthy … You Know !

Some External Stressors to GUT Health are : Consumption of NSAIDs / Antibiotics / Heavy Pharma / Birth Control Pills / Steroid Use, Poor Diet, Excessive Stress, Excessive Alcohol Consumption, Food Insensitivities. Viral Infections, Chronic Inflammation.

So, Let Your Body tell You How Long to maintain a STRESSed Level of GOOy CHEWy TUMMY.

Then, once your GUT has Stabilized, begin a WELL Daily amount to keep things that way. And, be ever watchful of Old Bad Gut Habits beginning to appear once again.

Of course, if your Compromised Health Status is Prolonged and continues to Erode due to external GUT / Health Stressors, it is always best to consult your Physician.

I’m taking Antibiotics. When do I take GOOy CHEWy TUMMY ?

GOOy CHEWy TUMMY suggests …

[] STRESSed Level 2 weeks Before Antibiotic Protocol.

[] STRESSed Level 2 weeks After Antibiotic Protocol.

[] WELL Level thereafter for Week.

As a general rule, GOOy CHEWy feels that a Daily Amount of TUMMY is a good way to keep Your GUT Healthy, and You Happy !

Of course, if your Compromised Health Status is Prolonged and continues to Erode due to external GUT / Health Stressors, it is always best to consult your Physician.

How long do I continue a daily WELL Amount of GOOy CHEWy TUMMY ?

As a general rule, GOOy CHEWy feels that a Daily Amount of TUMMY is a good way to keep Your GUT Healthy, and You Happy !

How can I tell if GOOy CHEWy TUMMY is Helping Me.

This is a very good Question.

Besides obvious Improvement Signs if you have GI Issues…

With Products such as GOOy CHEWy TUMMY, which are Supplements, it is Important to Understand that it’s Product / Health Focus is more Prevention Vs Treatment.

By this we mean, that with a Healthy / Balanced GOOy CHEWy TUMMY Gut, while you still will be UnHealthy / Sick every so often, you may find that the Intensity / Duration and Frequency of Illness is greatly lessened.

We would very much like to hear how things go with you.

Wishing You GOOy CHEWy TUMMY Health & Happiness.

G.I. / Gut Health & Quality of Life Information

Gut Balance = Health ?

When it comes to Gut Health, it is All about Balance.

When your gut is in tip-top shape, about 80-85 percent of bacteria are good guys and 15-20 percent are bad guys. You feel great, your body is strong and nimble, you rarely get sick, your energy is consistent, you poop like a champ, life is good. The healthy bacteria are free to do their job with ease. They assist with digestion, produce disease-fighting antibodies, crowd out bad bacteria and produce certain hormones, vitamins and nutrients.

But when theharmful bacteria stage a revolt, all hell breaks loose. They totally gum up the works and cause painful problems like inflammation and infection, which can then lead to health issues such as constipation, candida, allergies, arthritis, headaches, depression, autoimmune diseases and more.

Medications (especially antibiotics and antacids), environmental toxins and chemicals, stress and illness greatly affect the ratio of good to bad bacteria. When bacteria is wiped out indiscriminately, the good guys get mowed down, giving the bad guys a chance to increase their ranks.

Then…

Hello, Chronic Health Issues.

Enemies of a Healthy Gut.

With such a delicate Balance and so many ways for things to go wrong, it’s no wonder that so many of us are Sick.

Even in a perfect world, our Gut has a hard time keeping things balanced.

In the challenging circumstances of Real Life, there’s seemingly no end to the things that knock our Digestive Systems Off Balance.

They include:

A standard American Diet (SAD) that is low in fiber, rich in sugar, low in nutrients, and high in additives and chemicals, changing the ecosystem of our guts

Overuse of Medications, such as anti-inflammatories, antibiotics, acid-blocking drugs (see “The Dangers of Acid-Blocking Drugs,” below) and steroids, that disrupt the gut’s ability to stay in balance and do its job

Chronic Low-Grade Infections or Gut Imbalances with bacterial or yeast overgrowth, parasites, or even more serious gut infections

Exposure to Toxins, such as mercury and mold, that damage normal gut function

Lack of adequate Digestive Enzyme Function, which can be caused by acid-blocking medications or zinc deficiency

Chronic Stress, which can alter the gut’s nervous system, causing a leaky gut and changing the normal bacteria in the gut

How does the Use of Antibodies Effect the GUT Microbiome ?

How does the Use of Antibodies Effect the GUT Microbiome ?

The high price of antibiotic use: can our guts ever fully recover?

Maintaining proper balance of healthy gut flora is a crucial yet widely misunderstood component of human health. While the development of antibiotics has lengthened our lifespans, our excessive and inappropriate use of these drugs may be causing serious long-term consequences we are only now becoming fully aware of.

These consequences not only affect our individual health, but may even be causing permanent changes to the microflora of all people from generation to generation.

Martin Blaser’s recent (2011) article published in Nature highlights the potentially dangerous long-term consequences that arise from the rampant overuse of antibiotics. He argues that changes in our microbiota may even be promoting the transmission of deadly organisms, as one of the important roles of an intact microflora is to resist colonization by pathogenic organisms.

Blaser also points out that not only does the individual use of antibiotics cause permanent changes in the gut flora, but that infants born to women given antibiotics during pregnancy, or the 30% of children delivered via cesarean section, may be starting life with a significantly altered and insufficient level of friendly gut flora. This is a serious concern because lack of diversity in friendly gut bacteria has been shown to contribute to a large number of diseases and complications.

Unfortunately, even a single course of antibiotics can permanently alter the gut flora.

One study found that after a single treatment of intravenous antibiotics, fecal bacteria tests demonstrated a significant change in the variety of bacterial strains, and the development of the pathogen Clostridium difficile. C. difficilecolonization in the gut can lead to serious complications such as severe diarrhea and colitis.

Another study demonstrated that a short course of the antibiotic ciprofloxacin reduced the diversity of the intestinal microbiota, with significant effects on roughly one-third of the bacterial species. This study also found that while much of the diversity eventually recovered, there were still several species that failed to recover after six months, suggesting that even a short course of antibiotics may cause permanent changes to the community of friendly flora in the gut.

Antibiotics are known to cause diarrhea, which may be due to infection by antibiotic resistant pathogens such as salmonella, C. perfringens type A,Staphylococcus aureus, and possibly Candida albicans, as well the various metabolic consequences of reduced concentrations of fecal flora. These results suggests that disturbance of the normal intestinal flora following antibiotic use may be responsible for the overgrowth of dangerous pathogens.

Research also indicates that infants’ gut flora is significantly affected by cesarean delivery, which requires the administration of antibiotics to the mother. One study demonstrated significant changes in the primary intestinal flora of infants born through cesarean delivery, lasting at least six months. Primary colonization of the newborn’s sterile intestinal tract normally happens during vaginal birth, and it is unknown whether an infant born with inadequate or unbalanced colonization will ever develop normal intestinal flora without intervention.

While breastfeeding can help restore some of the natural balance to the microflora, only about 44.3% of American women breastfeed (with only 14.8% breastfeeding exclusively) for the full six months that is recommended. Furthermore, breastfeeding alone may not compensate for the changes in flora associated with cesarean sections, suggesting that many infants may be at an even greater disadvantage when it comes to the proper development of a healthy, functional digestive tract.

Research from diverse fields demonstrates the negative effects of gut dysbiosis and inadequate friendly flora on a variety of health outcomes.

For example, resident bacteria of the normal flora are involved in intestinal mucosal inflammation and patients with inflammatory bowel disease (IBD) have higher amounts of bacteria attached to their intestinal mucosa than do healthy people.

Patients with Crohn’s disease and ulcerative colitis are found to have reduced concentrations of fecal Lactobacillus and Bifdobacteria, which protect against pathogenic bacteria, increase mineral absorption and induce the production of growth factor in the gut.

An unbalanced microbiota in the gut is also a contributing factor in autoimmunity.

Infection with certain microbial pathogens can trigger autoimmune reactions in joints and other organs. The destruction of healthy gut flora can make the mucosal lining more susceptible to leakage, which some researchers believe is a precondition for developing autoimmunity. It is well-established that the balance of gut bacteria plays a key role in the formation of a proper immune response.

A lack of healthy gut bacteria is associated with allergies, IBD, and general autoimmune reactions when this immune modulation goes awry.

New research has linked changes in gut bacteria with obesity. One study found that the gut bacteria of obese subjects differs significantly in species type from lean subjects, and that low calorie diets, restricting either fat or carbohydrates, changed the gut flora and increased the abundance of the bacterial strains found more predominantly in the lean subjects. Another study found that transplanting fecal bacteria from lean or obese mice into mice with sterile guts could affect whether these mice gained body fat, even when food intake was controlled. Those mice implanted with fecal bacteria from obese mice gained a significantly larger percentage of body fat than those transplanted with bacteria from lean mice. The authors hypothesized that certain types of gut flora are associated with obesity due to the increased extraction of energy from the diet.

These studies demonstrate the wide range of potential consequences caused by the improper development or destruction of the intestinal flora.

Though antibiotics may be necessary in certain situations, it’s important to weigh the benefits of using them with the potential risks that may come from the permanent alteration of the gut flora. If antibiotics must be used (and there are certainly situations where this is the case), special care should be taken to not only restore their gut flora using probiotic foods and supplements, but to eat a diet that supports healthy gut microbiota with plenty of fermentable fibers from starch and the removal of food toxins.

To protect infants’ gut health, especially those infants born through cesarean section, it is crucial to exclusively breastfeed for at least six months, with breastfeeding continuing on-demand throughout the complementary feeding period (up to 2 years of age).

Altering the numbers of gut bacteria, for example by taking broad spectrum antibiotics, may affect the host’s health and ability to digest food.Antibiotics can cause antibiotic-associated diarrhea ( AAD ) by irritating the bowel, changing the levels of gut flora, or allowing Pathogenic bacteria to grow.Another harmful effect of antibiotics is the increase in numbers of antibiotic-resistant bacteria found after their use, which, when they invade the host, cause illnesses that are difficult to treat with antibiotics.

Changing the numbers and species of gut flora can reduce the body’s ability to ferment carbohydrates and metabolize bile acids and may cause diarrhea. Carbohydrates that are not broken down may absorb too much water and cause runny stools, or lack of SCFAs produced by gut flora could cause the diarrhea.

A reduction in levels of native bacterial species also disrupts their ability to inhibit the growth of harmful species such as C. Difficile and Salmonella Kedougou, and these species can get out of hand, though their overgrowth may be incidental and not be the true cause of diarrhea. Emerging treatment protocols for C. difficile infections involve fecal microbiota transplantation of donor feces. (see Fecal Transplant ) Initial reports of treatment describe success rates of 90%, with few side effects. Efficacy is speculated to result from restoring bacterial balances of bacteroides and firmicutes classes of bacteria.

Gut flora composition also changes in severe illnesses, due not only to antibiotic use but also to such factors as ischemia of the gut, failure to eat, and immune compromise. Negative effects from this have led to interest in selective digestive tract decontamination (SDD), a treatment to kill only pathogenic bacteria and allow the re-establishment of healthy ones.

For more than 50 years we have known that the administration of low doses of antibacterial agents promotes the growth of farm animals to increase weight gain.

Antibiotics alter the population of the GI (gastrointestinal tract is the stomach and intestine, sometimes including all the structures from the mouth to the anus) microbiota may change the intra-community metabolic interactions, modify caloric intake by using carbohydrates, and globally affects host metabolic, hormonal and immune homeostasis.

In a study performed on mice by Ilseung Cho, the ratio of Firmicutes and Lachnospiraceae was significantly elevated in animals treated with subtherapeutic doses of different antibiotics. By analyzing the caloric content of faeces and the concentration of small chain fatty acids (SCFAs) in the GI tract, they concluded that the changes in the composition of microbiota lead to an increased capacity to extract calories from otherwise indigestible constituents, and to an increased production of SCFAs. These findings provide evidence that antibiotics perturb not only the composition of the GI microbiome but also its metabolic capabilities, specifically with respect to SCFAs.

Antibiotics and maintaining Healthy GUT MicroBiome.

Antibiotics are truly a wonder of modern medicine.

Beginning with the discovery of penicillin by Alexander Fleming in 1928, the pure magic of antibiotics with their rapid resolution of bacterial infections of all kinds caused many in the medical profession to become completely enamored with the drug based approach to illness. By 1940, antibiotics had come into widespread use causing both doctors and people to gradually forget about tried and true techniques for preventing illness such as the age old remedy cod liver oil.

This change in the medical paradigm has led in recent decades to abuse of these magical meds and the growing threat of antibiotic resistant bacterial strains. It has also caused in an epidemic of people with compromised gut function due to an imbalanced intestinal environment resulting from excessive exposure to antibiotics via industrially produced foods, medicine, and more recently, groundwater contamination.

While antibiotics clearly have their place in treating life threatening bacterial infections, their overuse has led to a plethora of modern day health challenges and autoimmune disease.

While complete avoidance of all antibiotic exposure would be the ideal, it is simply not practical in the majority of cases. Sometimes, antibiotics are necessary and when such a situation arises, it is imperative to protect the gastrointestinal tract from fungal or yeast overgrowth during treatment and to replenish beneficial gut bacteria when the course of antibiotics is complete.

While antibiotics effectively kill both pathogenic and beneficial bacteria with the exception of antibiotic-resistant species of streptococcus and other strains, they do not affect the many forms of yeast such as Candida albicans naturally found in the body in a nondominant role.

As beneficial bacteria lining the gut wall are eliminated, yeasts like Candida albicans have the opportunity to overgrow and become dominant by attaching to the gut wall. Once attached to the gut wall, yeast has the ability to create lesions in the cell membranes. This can lead to the syndrome referred to as “Leaky Gut”, which increases the likelihood of foreign proteins entering the bloodstream resulting in inflammation, food intolerances, a myriad of digestive problems, autoimmune disease, and other associated imbalances.

Please note that these recommendations are helpful whether the antibiotic treatment came from oral medication or IV treatment. Even IV antibiotics damage gut flora despite the fact that the medication does not make its way directly through the intestinal environment like oral meds do.

Suggestion;

Prebiotic & Probiotic Support > Before / During / After Antibiotic Protocols.

With daily Pre & Probiotic replenishment as deemed appropriate by your everyday health status.

SIX Factors Behind GUT Imbalance.

The lethal implications for the link between gut imbalance and increased disease risks are clear.

But what factors are behind this dangerous imbalance?

The answer is that accompanying the rise in a number of diseases in Western societies is the increased influence of a host of factors that continually disrupt our natural gut bacteria balance.

Antibiotics. One cause of an imbalance between good-to-bad bacteria is the unnecessary use of antibiotics.Antibiotic use, even at low sub-therapeutic doses, can disrupt the number and relative proportions of gut bacteria.

Infant formula. Common use of infant formula instead of breast milk has interfered with mankind’s long history of transferring bacterial diversity from mother to baby.Similarly,Caesariandelivery prevents babies from inheriting diverse bacteria from their mothers.

Excessive hygiene. An exploding obsession with hygiene has drastically reduced our ability to naturally acquire certain key bacteria from our environment.

Western Diet. The WesternDiet—high in animal proteins and fats, sugars, and refined carbohydrates—causes a rise in undesirable bacteria, not counterbalanced by those that hold them at ideal levels.

This dietary shift has resulted in changes to metabolic pathways within the gut bacterial ecosystem and altered bacterial gene expression.Much of the food in the Western diet is made up of refined carbohydrates, which are absorbed in the upper part of the gastrointestinal tract.What eventually reaches the large intestine is of limited value to microbiota in this area because it contains only small amounts of the minerals, vitamins, and other nutrients necessary to maintain them.As a result, the numbers and diversity of beneficial intestinal bacteria of modern humans is greatly reduced, compared to the diets of Paleolithic man.

Modern Medical Treatments. A number of modernmedicaltreatments are known to severely impair the proper balance of gut bacteria.These include artificial ventilation, hygienic measures, use of skin-penetrating devices, tubes and catheters, frequent pharmaceutical use, and more.

6 Age. Recent findings suggest that aging disrupts the bacterial makeup of the gut. This imbalance may contribute to the age-related increase in inflammation known as “InflammAging.”

NSAIDs ?

Chronic Inflammation

Immune System Over-Load = Chronic Inflammation = AutoImmune Diseases

Chronic Inflammation is an Immune System Reaction on a Cellular level to an Irritant / Allergen.

Chronic Inflammation is Health’s most pervasive Adversary

Creating a Toxic Effect on almost every Single Tissue / Organ in the Human Body.

The use of NSAIDs for pain management, put the body into an unbalanced state of inflammation.

You may not think that occasional ibuprofen or aspirin use is not a big deal. It is a big deal. If you did not catch the statements about NSAIDS and adverse effects, you need to hear it again. There are serious adverse effects that can occur without warning, including GI bleed, ulcers, heart attack, and even death. This applies to all ages of NSAIDS users including the 70 year old with bad knees, the 40 year old with migraines, and the banged up, sports playing teenager.

The NSAIDS Ibuprofen, and Naproxen actually come with a “Black Box” warning because of these potentially life threatening adverse effects. It is known that properly prescribed NSAIDS cause roughly 20,000 deaths and well over 100,000 hospitalizations EACH year.

Also consider this, it has been known since the 1970s that NSAIDS actually increase the breakdown of cartilage cells building blocks – glycoaminoglycans (GAGs). GAGs help cartilage hold onto water and function as a shock absorber. They are essential for cartilage function and preventing its break down. So in using these NSAIDS, your pain may be less while the inflammatory pathway is blocked, but what happens when the drug is metabolized out of the system? The cartilage building blocks have further deteriorated, so the pain comes back. Not only does the pain come back, but there is more destruction in the cartilage. It becomes a vicious cycle of damage and destruction when on this path. This is obviously not a path that you want to be on.

Why GUT Health is Important.

Healthy GUT ?

There is no health without healthy gut.

Your GUT has three functions crucial to your health:

(1) it breaks food down to nutrients,

(2) facilitates their Absorption into the blood through intestinal walls, and

(3) prevents foreign and toxic molecules from entering the bloodstream.

Add to it that healthy intestine has a major role in Detoxification by neutralizing or breaking down toxins ingested with food (by good intestinal bugs, so called Probiotics as well as in the intestinal cell’sand it becomes clear that any gut malfunction will adversely affect health.

You can have the Best Foods, low exposure to toxins to Toxins and brightest attitude – if your digestion, nutrient absorption and gut-detoxification are not functioning properly, your health will deteriorate.

GOOy CHEWy Business Information

Does GOOy CHEWy have a Sample Program for HONEY plus TUMMY ?

While it is normal to ask if SAMPLEs are available, especially given the fact that GOOy CHEWy is

Not a Casual Purchase, there is NOT a Sample Program for GOOy CHEWy TUMMY.

Typically, when Customers ask for SAMPLEs, it is for the following Two Reasons.

#1) They want to see what it Taste Like.

#2) They want to see if the Product “Works”.

To these Two Points, Please find the following reply:

#1) The Customer wants to see what it Taste Like.

In the case of GOOy CHEWy TUMMY, because it is a Honey-Based Confectionary, it is Important that You “Like” Honey. And that You “ Like” a GOOy Type of Confectionery.

If Yes, You are good to GOoy, if Not, You will Not Like GOOy CHEWy TUMMY.

#2) The Customer wants to see if the Product “Works”.

To address this Question / Request, it is Important to understand a number of points:

#1) GOOy CHEWy is Not a Drug, it is a Health Supplement. And as such, can not Claim to Diagnose, Mitigate, Treat, Cure or Prevent Disease.

As such, when you examine GOOy CHEWy’s “Health Focus” i.e. Building GUT Health & Balance, it is Not Possible for GOOy CHEWy to actually “Say” that it works to Mitigate, Treat, Cure or Prevent your Allergy Disease.

Does GOOy CHEWy have a Guarantee for HONEY plus TUMMY ?

GOOy CHEWy TUMMY can not offer any Guarantee.

To begin, GOOy CHEWy TUMMY is Not a Drug, it is a Health Supplement. And as such, cannot Claim to Diagnose, Mitigate, Treat, Cure or Prevent Disease.

As such, when you examine GOOy CHEWy’s “Health Focus” i.e. Building a Healthy / Balanced GUT, it is Not Possible for GOOy CHEWy to actually “Say” that it works to Mitigate, Treat, Cure or Prevent your Allergy Disease.

Further, because everyone’s health profile and extent of allergy entrenchment is different. And that may co-Factors come into play regarding the resolution of a GUT / GI Health status, GOOy CHEWy Can Not make Any Claims of Guarantee.

However, when all is said and done, GOOy CHEWy feels that it is certainly worth a try …

You just might be Pleasantly Surprised !

Is HONEY plus TUMMY a FDA Approved Drug, which can Claim to Diagnose, Treat, Cure or Mitigate Disease ?

No …

GOOy CHEWy TUMMY is a Supplement, Not a Drug and can not Claim to Cure, Diagnose of Mitigate any Disease.

Statements are not meant to Replace the Medical Advice of your Physician.

Statements made by GOOy CHEWy are not based on Clinical Study Trials, but rather a belief of the Principals / Ingredients involved.

All Information / Material stated on the GOOy CHEWy website is for informational purposes only. Readers are encouraged to confirm the information contained herein with other sources. Patients and consumers should review the information carefully with their professional health care provider. The information is not intended to replace medical advice offered by physicians. GOOy CHEWy is not be liable for any direct, indirect, consequential, special, exemplary, or other damages arising therefrom.

The Content is presented in summary form, is general in nature and is provided for informational purposes only. GOOy CHEWy strongly advise that you consult your health care provider before you begin any GOOy CHEWy Product. The information provided herein is meant to supplement the advice and counsel of your health care provider or other health professionals. The information provided with respect to the Content is not meant to substitute for medical advice from your health care provider. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition. Neither the Content nor any other Product(s) offered by or through the Site, is intended to be relied upon for medical diagnosis or treatment. Never disregard, or delay in seeking, medical advice because of your use or interpretation of the Content.

GOOy CHEWy reserve the right to refuse the Sale of any GOOy CHEWy Products to any Individual for any reason, including certain medical conditions.

Visitors to the Site is accepted solely at your own risk. GOOy CHEWy assume no liability or responsibility for damage or injury to persons or property arising from any use of any product, information, idea or instruction contained in the materials provided to you. GOOy CHEWy reserves the right to change or discontinue at any time any aspect or feature of the Site.

The Content comes from sources believed to be accurate, but may contain inaccuracies or typographical errors. GOOy CHEWy make no representations about the results to be obtained from using the Site or the Content. The use of the Site and the Content is at your own risk.

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You are advised that health advice is often subject to updating and refining due to medical research and developments. No assurance can be given that the Content will reflect the most recent findings or developments with respect to the particular material. You are encouraged to consult with your health care provider with any questions or concerns you may have regarding any health condition.